Reporting cases by clinical laboratories - 28 Pa. Code § 27.22

The following diseases, infections, conditions and results must be promptly reported upon discovery by a clinical laboratory in the course of performing requested tests on specimens submitted by providers:

• Amebiasis;
• Anthrax;
• An unusual cluster of isolates;
• Arboviruses;
• Botulism;
• Brucellosis;
• CD4 T-lymphocyte test result with a count of less than 200 cells/µL or a CD4 T-lymphocyte percentage of less than 14% of total lymphocytes*;
• Campylobacteriosis;
• Cancer*;
• Chancroid;
• Chickenpox (varicella);
• Chlamydia trachomatis infections;
• Cholera;
• Congential adrenal hyperplasia (CAH) in children under 5 years of age*;
• Creutzfeldt-Jakob disease;
• Cryptosporidiosis;
• Diphtheria;
• Enterohemorrhagic E. coli 0157 infections or infections caused by other subtypes producing shiga-like toxin;
• Galactosemia in children under 5 years of age*;
• Giardiasis;
• Gonococcal infections;
• Granuloma inguinale;
• HIV (Human Immunodeficiency Virus)*;
• Haemophilus influenzae infections – invasive form sterile sites;
• Hantavirus;
• Hepatitis, viral, acute or chronic cases;
• Histoplasmosis;
• Influenza;
• Lead poisoning*;
• Legionellosis;
• Leprosy (Hansen’s disease);
• Leptospirosis;
• Listeriosis;
• Lyme disease;
• Lymphogranuloma venereum;
• Malaria;
• Maple syrup urine disease (MSUD) in children under 5 years of age*;
• Measles (rubeola);
• Meningococcal infections – invasive from sterile sites;
• Mumps;
• Pertussis (whopping cough);
• Phenylketonuria (PKU) in children under 5 years of age*;
• Primary congenital hypothyroidism in children under 5 years of age*;
• Plague;
• Poliomyelitis;
• Psittacosis (ornithosis);
• Rabies;
• Respiratory syncytial virus;
• Rickettsial infections;
• Rubella;
• Salmonella;
• Shigella;
• Sickle cell disease in children under 5 years of age*;
• Staphylococcus aureus Vancomycin-resistant (or intermediate) invasive disease;
• Streptococcus pneumoniae, drug-resistant invasive disease;
• Syphilis;
• Tetanus;
• Toxoplasmosis;
• Trichinosis;
• Tuberculosis, confirmation of positive smears or cultures, including results of drug susceptibility testing;
• Tularemia; and
• Typhoid.

Unless otherwise indicated, the report must be submitted through secure electronic mechanisms to the department of health’s bureau of epidemiology and include the name, age, address and telephone number of the person from whom the specimen was obtained and the results of the test, unless otherwise specified.

Note: All conditions and test results marked with an asterisk (*) must be reported by a clinical laboratory upon discovery, but may be subject to different reporting requirements than the others listed under certain circumstances.